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TranscriptomicsComparative analysis of monocytes from healthy donors, patients with metastatic breast cancer, sepsis or tuberculosis.
Myeloid-derived suppressor cells (MDSCs) are highly immunosuppressive myeloid cells, which increase in cancer patients. The molecular mechanism behind their generation and function is unclear. Whereas granulocytic-MDSCs correlate with poor overall survival in breast cancer, the presence and relevanc...
ORGANISM(S): Homo sapiens 
2015-02-03 | E-GEOD-65517 | biostudies-arrayexpress
TranscriptomicsThe HER2-encoded miR-4728-3p regulates ESR1 through a non-canonical internal seed interaction
Since the early 1980s remarkable progress has been made in understanding the role of the HER2 locus in carcinogenesis, but many details of its regulatory network are still elusive. We recently reported the finding of 367 new human microRNA (miRNA) genes of which one, mir-4728, is encoded in an intro...
ORGANISM(S): Homo sapiens 
2014-08-13 | E-GEOD-55822 | biostudies-arrayexpress
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