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ModelsDallePezze2014 - Cellular senescene-induced mitochondrial dysfunction
DallePazze2014 - Cellular senescene-induced mitochondrial dysfunction This model is described in the article: Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions. Dalle Pezze P, Nelson G, Otten EG, Korolchuk VI, Kirkwood TB, von...
2024-09-02 | BIOMD0000000582 | BioModels
ModelsPassos2010_DNAdamage_CellularSenescence
This is the model described in: Feedback between p21 and reactive oxygen production is necessary for cell senescence. Passos JF, Nelson G, Wang C, Richter T, Simillion C, Proctor CJ, Miwa S, Olijslagers S, Hallinan J, Wipat A, Saretzki G, Rudolph KL, Kirkwood TB, von Zglinicki T. ;M...
2024-09-02 | BIOMD0000000287 | BioModels
UnknownNeutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner.
Cellular senescence is characterized by an irreversible cell-cycle arrest as well as a pro-inflammatory phenotype, thought to contribute to aging and age-related diseases. Neutrophils have essential roles in inflammatory responses; however, in certain contexts their abundance is associated with a nu...
S-SCDT-EMBOJ-2020-106048P | biostudies-other
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