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E-MTAB-6255

ABSTRACT: RNA-seq of adipose tissue from pigs divergent in feed efficiency reveals variations in adipose growth, extracellular matrix formation, lipid metabolism and immune response

PROVIDER: E-MTAB-6255 | ExpressionAtlas | 2019-09-09

REPOSITORIES: ExpressionAtlas

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RNA-seq of adipose tissue from pigs divergent in feed efficiency reveals variations in adipose growth, extracellular matrix formation, lipid metabolism and immune response

Project description:RNA-seq of adipose tissue from pigs divergent in feed efficiency reveals variations in adipose growth, extracellular matrix formation, lipid metabolism and immune response

| PRJEB23654 | ENA

RNA-seq of adipose tissue from pigs divergent in feed efficiency reveals variations in adipose growth, extracellular matrix formation, lipid metabolism and immune response

Project description:Feed efficiency (FE) is an indicator of efficiency in converting energy, attained from macronutrient ingestion, into tissue. Adipose tissue, besides being a master regulator of systemic lipid storage, is also an active endocrine organ that communicates with skeletal muscle, liver and brain to influence appetite, lipid & glucose metabolism and energy homeostasis. Adipose tissue is hypothesised to play a vital part in regulation of FE. The objective of the present study was to sequence the subcutaneous adipose tissue transcriptome in FE-divergent pigs (n=16) and identify relevant biological processes underpinning observed differences in FE.

2018-11-14 | E-MTAB-6255 | biostudies-arrayexpress

RNA-seq of liver from pigs divergent in feed efficiency highlights shifts in macronutrients metabolism, hepatic growth and immune response

Project description:Liver is a metabolically complex organ that influences nutrient partitioning and potentially modulates the efficiency of converting energy acquired from macronutrients ingestion into a muscle and/or adipose tissue (referred to as feed efficiency, FE). The objective of this study was to sequence the hepatic tissue transcriptome of pigs divergent for FE and identify relevant biological processes that underpin the differences in liver phenotypes and FE.

2019-02-11 | E-MTAB-6256 | biostudies-arrayexpress

E-MTAB-6256

Project description:RNA-seq of liver from pigs divergent in feed efficiency highlights shifts in macronutrients metabolism, hepatic growth and immune response

2020-07-23 | E-MTAB-6256 | ExpressionAtlas

Gene expression data of the subcutaneous adipose tissue from entire male, immunocastrated and surgically castrated pigs

Project description:Differences in adipose tissue deposition and properties between pig male sex categories, i.e., entire male, immunocastrated and surgically castrated pigs are relatively well characterized, whereas the underlying genetic mechanisms are still not fully understood. To gain the knowledge about the genetic regulation of the differences in adipose tissue deposition, RNA-sequencing approach was used. A total of 83 differentially expressed genes were identified between entire male and immunocastrated pigs, 15 between immunocastrated and surgically castrated pigs and 48 between entire male and surgically castrated pigs by RNA-sequencing of the subcutaneous adipose tissue. Comparing entire male with immunocastrated or surgically castrated pigs, upregulated genes related to extracellular matrix dynamics, and downregulated genes involved in the control of lipid and carbohydrate metabolism were determinated. Moreover, differential gene expression in general indicated a high similarity between immunocastrated and surgically castrated pigs in contrast to entire males, except for several heat shock protein genes which were upregulated in entire male and immunocastrated pigs compared with surgically castrated pigs.

2021-03-03 | GSE164391 | GEO

Ileal transcriptome profiles of pigs divergent in feed efficiency

Project description:in vivo microarray study of transcriptional changes of ileum (mucosa) obtained from pigs divergent in feed efficiency

2020-04-28 | GSE142434 | GEO

Caecal transcriptome profiles of pigs divergent in feed efficiency

Project description:in vivo microarray study of transcriptional changes of caecum (mucosa) obtained from pigs divergent in feed efficiency

2020-04-28 | GSE142433 | GEO

Hypothalamic transcriptome profiles of pigs divergent in feed efficiency

Project description:in vivo microarray study of transcriptional changes of the hypothalamus obtained from pigs divergent in feed efficiency.

2018-12-21 | GSE109334 | GEO

Ileal transcriptome profiles of pigs divergent in feed efficiency

Project description:in vivo microarray study of transcriptional changes of ileal scratchings (mucosa) obtained from pigs divergent in feed efficiency.

2018-12-21 | GSE109333 | GEO

Jejunal transcriptome profiles of pigs divergent in feed efficiency

Project description:in vivo microarray study of transcriptional changes of jejunal scratchings (mucosa) obtained from pigs divergent in feed efficiency.

2018-12-21 | GSE109332 | GEO

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