Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-MTAB-6796

ABSTRACT: Transcriptional response to Rosiglitazone in adipocyte progenitors isolated from WT and Cited4-KO scWAT

PROVIDER: E-MTAB-6796 | ExpressionAtlas | 2018-05-23

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-MTAB-6796-analysis-methods.tsv	Tabular
	E-MTAB-6796-atlasExperimentSummary.Rdata	Rdata
	E-MTAB-6796-configuration.xml	Xml
	E-MTAB-6796-percentile-ranks.tsv	Tabular
	E-MTAB-6796.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 74

Similar Datasets

Microarray data of Atg5 WT and KO hematopoietic stem/progenitor cells

Project description:To comprehensively examine differences of gene expression patterns between WT and ATG5 KO HSCs/progenitors, we isolated LSK cells and conducted the microarray analysis.

2021-01-20 | GSE153613 | GEO

Microarray data of Spred1 WT and KO hematopoietic stem/progenitor cells

Project description:To comprehensively investigate differences of gene expression patterns between Spred1 WT and KO HSCs/progenitors, we isolated HSCs/progenitor cells and performed the microarray analysis.

2018-04-26 | GSE85225 | GEO

Single-cell RNA-seq of Fibroadipogenic progenitors from WT and Dysferlin KO mice

Project description:Droplet-based single-cell RNA-seq of fibroadipogenic progenitors (FAPs) isolated from whole limb skeletal muscles of 8 month old WT and Dysferllin KO mice.

2022-12-31 | GSE182293 | GEO

Transcriptional profiling of colonic Regulatory T (Treg) cells, CD4+ conventional T (Tconv) cells, dendritic cells (DCs), and epithelial cells (ECs) from Vdr WT- or Vdr KO-Foxp3 reporter mice

Project description:We reported transcriptional characterization of Treg cells, Tconv cells, and DCs isolated from coloinc lamina propria of Vdr WT- or Vdr KO-Foxp3 reporter mice. We also reported transcriptional characterization of colonic ECs isolated from Vdr WT- or Vdr KO-Foxp3 reporter mice.

2019-12-31 | GSE137405 | GEO

mRNA expression of murine hematopoietic stem cells and ex vivo murine MLL-AF9 cells deficient for total PRDM16 or f-PRDM16, and AF9 cells overexpressing individual PRDM16 isoforms

Project description:Group 1 -- WT or PRDM16-KO ex vivo murine MLL-AF9 cells, and PRDM16-KO AF9 cells overexpressing either f-PRDM16 or s-PRDM16. Group 2 -- WT or total PRDM16-KO murine HSCs isolated from adult BM. Group 3 -- WT or total PRDM16-KO murine HSCs isolated from fetal liver. Group 4 -- WT or f-PRDM16-KO murine HSCs (expressing s-PRDM16 only) isolated from fetal liver.

2018-06-08 | GSE112860 | GEO

Regnase-1 KO CAR T cell reprogramed to memory-like cells

Project description:transcriptional profiling was performed on WT and KO CAR T cells isolated 21 days after co-transfer into tumor bearing mice. Regnase-1 KO CAR T cell reprogramed to memory-like cells long-term after tumor priming in vivo compared to WT CAR T cells

2021-07-08 | GSE154942 | GEO

Analysis of histone variant H2BE in neuronal chromatin

Project description:WT and H2BE-KO primary cortical neurons were isolated from E16.5 mice and culture for 12 days for ATAC-sequencing (n=3 WT biological replicates, 4 KO biological replicates).

2024-07-17 | GSE246687 | GEO

Galectin-3 Deficiency Exacerbates Hyperglycemia and the Endothelial Response to Diabetes

Project description:Microarray analyses were performed in order to determine the effect of galectin-3 ablation on the endothelial transcriptional response in a mouse model of type 2 diabetes. Galectin-3-deficient mice (KO) and wild-type C57BL/6 (WT) were fed a high-fat diet (60% fat calories) or standard chow for 8 weeks. CD105+/CD45- endothelial cells were isolated from the aortae and skeletal muscles of these mice by FACS. Whole genome microarray expression profiling revealed greater transcriptional dysregulation in the endothelium of the KO after high-fat feeding compared to WT. Transcripts dysregulated in the KO endothelium after HFD include those involved in glucose uptake and insulin signaling, oxidative stress, vasoregulation, coagulation, and atherogenesis. Real-time PCR confirmed transcriptional downregulation of the glucose transporter, Glut4, and immunofluorescence staining confirmed reduced GLUT4 protein in the endothelium and mudcle of the KO compared to WT. The transcriptional and histological data was consistent with physiological studies showing exacerbated hyperglycemia and coagulation in the KO. These results suggest that galectin-3 serves a protective role against metabolic dysregulation and endothelial dysfunction in diabetes.

2015-08-01 | GSE57329 | GEO

Metabolomics Analysis of the Effect of GAT-2 Deficiency on Th1 Cells in Mice

Project description:<p>The classic neurotransmitter gamma-aminobutyric acid (GABA) has been shown to shape the activation and function of immune cells. There are four high affinity GABA transporters (GATs, including GAT-1, GAT-2, GAT-3 and GAT-4) responsible for the transmembrane transport of GABA in mice. To explore the effect of GAT-2 on type 1 helper T (Th1) cells, naïve CD4+ T cells were isolated from splenocytes of GAT-2 knockout (KO) and wild-type (WT) mice and cultured for Th1 cell differentiation, and then metabolomics analysis of Th1 cells was performed via gas chromatography coupled to time-of-flight mass spectrometry (GC-TOF-MS) added with multivariate analyses. The study will provide insights into T cell response to GAT-2 deficiency in mice.</p>

2021-10-14 | MTBLS3358 | MetaboLights

Regnase-1 suppresses TCF-1+ precursor exhausted T cell formation to limit CAR T cell responses against ALL [Microarray Expression]

Project description:transcriptional profiling was performed on WT and KO CAR T cells isolated 7 days after co-transfer into mice with or without tumors. Regnase-1 KO CAR T cells undergoing a tumor-dependent shift from an effector to memory-like phenotype

2021-07-08 | GSE154859 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data