Transcriptomics,Multiomics

Dataset Information

10

Transcription and microRNA profiling of three types of breast tumors, benign fibroadenoma and fibroadenomatosis, and malignant breast carcinoma


ABSTRACT: In this study we have preformed miRNA and mRNA expression profiling of benign breast tumors, breast cancers, and normal breast tissue. We have identified cancer-related miRNAs in benign tumors, with their deregulation similar to that in cancer tissue. In addition we have performed miRNA-mRNA correlation studies.

REANALYSIS of: E-MTAB-779

ORGANISM(S): Homo sapiens  

DISEASE(S): fibroadenomatosis,breast carcinoma,fibroadenoma

PROVIDER: E-MTAB-779 | ExpressionAtlas | 2015-08-27

REPOSITORIES: ExpressionAtlas

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Publications


MicroRNAs (miRNAs) are endogenous non-coding RNAs, which play an essential role in the regulation of gene expression during carcinogenesis. The role of miRNAs in breast cancer has been thoroughly investigated, and although many miRNAs are identified as cancer related, little is known about their involvement in benign tumors. In this study, we investigated miRNA expression profiles in the two most common types of human benign tumors (fibroadenoma/fibroadenomatosis) and in malignant breast tumors  ...[more]

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