Ontology highlight
ABSTRACT:
SUBMITTER:
Enuo He
PROVIDER: BIOMD0000000086 | BioModels | 2024-09-02
REPOSITORIES: BioModels
Items per page: 1 - 5 of 16 |

Proceedings of the National Academy of Sciences of the United States of America 20041101 45
Heterotrimeric G protein signaling is regulated by signaling modules composed of heterotrimeric G proteins, active G protein-coupled receptors (Rs), which activate G proteins, and GTPase-activating proteins (GAPs), which deactivate G proteins. We term these modules GTPase-cycle modules. The local concentrations of these proteins are spatially regulated between plasma membrane microdomains and between the plasma membrane and cytosol, but no data or models are available that quantitatively explain ...[more]