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Zeilinger2006_PRR7-PRR9light-Y


ABSTRACT: The model reproduces the time profile of cYm and cTm under light-dark cycles as depicted in Fig 4 and Fig 5 respectively. 12 hour light-dark cycles are accomplished using a simple algorithm in the event section. The model was successfully tested using MathSBML. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.

SUBMITTER: Molecular Systems Biology  

PROVIDER: BIOMD0000000096 | BioModels | 2007-03-03

REPOSITORIES: BioModels

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Publications

A novel computational model of the circadian clock in Arabidopsis that incorporates PRR7 and PRR9.

Zeilinger Melanie N MN   Farré Eva M EM   Taylor Stephanie R SR   Kay Steve A SA   Doyle Francis J FJ  

Molecular systems biology 20061114


In plants, as in animals, the core mechanism to retain rhythmic gene expression relies on the interaction of multiple feedback loops. In recent years, molecular genetic techniques have revealed a complex network of clock components in Arabidopsis. To gain insight into the dynamics of these interactions, new components need to be integrated into the mathematical model of the plant clock. Our approach accelerates the iterative process of model identification, to incorporate new components, and to  ...[more]

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