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Panteleev2002_TFPImechanism_schmema3

ABSTRACT: This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. For more information see the terms of use. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.

SUBMITTER: Michael Schubert

PROVIDER: BIOMD0000000359 | BioModels | 2024-09-02

REPOSITORIES: BioModels

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			Action	DRS
	BIOMD0000000359?filename=BIOMD0000000359-biopax2.owl	Owl
	BIOMD0000000359?filename=BIOMD0000000359-biopax3.owl	Owl
	BIOMD0000000359?filename=BIOMD0000000359-matlab.m	Other
	BIOMD0000000359?filename=BIOMD0000000359-octave.m	Other
	BIOMD0000000359?filename=BIOMD0000000359.m	Other

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Publications

Tissue factor pathway inhibitor: a possible mechanism of action.

Panteleev Mikhail A MA Zarnitsina Veronica I VI Ataullakhanov Fazoil I FI

European journal of biochemistry 20020401 8

We have analyzed several mathematical models that describe inhibition of the factor VIIa-tissue factor complex (VIIa-TF) by tissue factor pathway inhibitor (TFPI). At the core of these models is a common mechanism of TFPI action suggesting that only the Xa-TFPI complex is the inhibitor of the extrinsic tenase activity. However, the model based on this hypothesis could not explain well all the available experimental data. Here, we show that a good quantitative description of all experimental data ...[more]

PMID: 11985578

Publication: 1/2

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