Colonization, luminescence, and autoinducer effects on host transcription during development of squid-vibrio association

ABSTRACT: The light-organ symbiosis between the squid Euprymna scolopes and the luminous bacterium Vibrio fischeri offers the opportunity to decipher the hour-by-hour events that occur during the natural colonization of an animal's epithelial surface by its microbial partners. To determine the genetic basis of these events, a glass-slide microarray was used to characterize the light-organ transcriptome of juvenile squid in response to the initiation of symbiosis. Patterns of gene expression were compared between animals not exposed to the symbiont, exposed to the wild-type symbiont, or exposed to a mutant symbiont defective in either of two key characters of this association: bacterial luminescence or autoinducer (AI) production. Hundreds of genes were differentially regulated as a result of symbios

ORGANISM(S): Euprymna scolopes

SUBMITTER: Bartley Brown 

PROVIDER: E-GEOD-13533 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress