Transcription profiling of human patients with allergy to latex and/or vegetable food

ABSTRACT: Background: The prevalence of individuals allergic to latex, exhibiting cross-hypersensitivity with plant-derived food has been frequently reported as the so-called latex-fruit syndrome. Nonetheless, molecular mechanisms underlying allergy to latex and/or fruit are poorly understood. Objective: The aims of this study were to identify candidate genes that may be associated with the pathogenesis of allergy to latex and /or vegetable food, and to assess if similar molecular pathways are involved in both types of hypersensitivity. Methods: DNA microarray analysis was performed to screen the molecular profiles of peripheral blood mononuclear cells isolated from patients with allergy to latex, to fruit, or with latex-fruit syndrome, and from control healthy subjects. Results: Gene expression pr

ORGANISM(S): Homo sapiens

SUBMITTER: Nathalie Saulnier 

PROVIDER: E-GEOD-13619 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress