MicroRNA identity and abundance in porcine skeletal muscles determined by deep sequencing

ABSTRACT: MicroRNAs (miRNA) are short single-stranded RNA molecules that regulate gene expression post-transcriptionally by binding to complementary sequences in the 3' untranslated region (3' UTR) of target mRNAs. MiRNAs participate in the regulation of myogenesis, and identification of the complete set of miRNAs expressed in muscles is likely to significantly increase our understanding of muscle growth and development. To determine the identity and abundance of miRNA in porcine skeletal muscle, we applied a deep sequencing approach. This allowed us to identify the sequences and relative expression levels of 212 annotated miRNA genes, thereby providing a thorough account of the miRNA transcriptome in porcine muscle tissue. The expression levels displayed a very large range, as reflected by the numb

ORGANISM(S): Sus scrofa

SUBMITTER: Jakob Hedegaard 

PROVIDER: E-GEOD-14584 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress