Gene Expression Atlas for Human Embryogenesis

ABSTRACT: Gene expression profiling has provided critical insights into the molecular pathways underlying development of model organisms, however little information is available on regulated gene expression during human embryogenesis. We have now filled this important gap of knowledge by performing genome-wide microarray analysis of the Homo sapiens gene expression during the 4-9th week, a period when most organs develop. We analyzed individually 3 embryos for each of the 4th, 5th, 6th, 7th, 8th, and 9th week of human embryonic development by using the Affymetrix U133 plus 2.0 human GeneChip array.About half of all human genes are expressed and 18.6% of the expressed genes were significantly regulated during this important period. We further identified over 5000 regulated genes, most of which were p

ORGANISM(S): Homo sapiens

SUBMITTER: Wenxin Li 

PROVIDER: E-GEOD-15744 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress