Transcriptional response of Rhodococcus aetherivorans I24 to polychlorinated biphenyl contaminated sediments

ABSTRACT: We analyzed the transcriptional response of the actinomycete Rhodococcus aetherivorans I24 to biphenyl and polychlorinated biphenyls (PCBs). This species has not been extensively exposed to PCBs, as it was first isolated from a toluene contaminated aquifer, rather than a site contaminated with polychlorinated hydrocarbons. Using a microarray targeting 3524 genes, we assessed gene expression in minimal medium supplemented with various substrates (e.g. PCBs) and in both PCB-contaminated and non-contaminated sediment slurries. Relative to the reference condition (minimal medium supplemented with glucose), 408 genes were up-regulated in the various treatments. In medium and in sediment, PCBs elicited the up-regulation of a common set of 100 genes, including chaperones (groEL), a superoxide di

ORGANISM(S): Rhodococcus aetherivorans

SUBMITTER: Ettore Capri 

PROVIDER: E-GEOD-17033 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress