Gene expression profile of mesenchymal stem cells from paired umbilical cord units: cord is different from blood

ABSTRACT: Mesenchymal stem cells (MSC) are multipotent cells which can be obtained from several adult and fetal tissues including human umbilical cord units. We have recently shown that umbilical cord tissue (UC) is richer in MSC than umbilical cord blood (UCB) but their origin and characteristics in blood as compared to the cord remains unknown. Here we compared, for the first time, the exonic protein-coding and intronic noncoding RNA (ncRNA) expression profiles of MSC from match-paired UC and UCB samples, harvested from the same donors, processed simultaneously and under the same culture conditions. The patterns of intronic ncRNA expression in MSC from UC and UCB paired units were highly similar, indicative of their common donor origin. The respective exonic protein-coding transcript expression

ORGANISM(S): Homo sapiens

SUBMITTER: Yuri Moreira 

PROVIDER: E-GEOD-18134 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress