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Gene expression profiling of aortic media after long-term treatment with an angiotensin II-receptor blocker, Losartan

ABSTRACT: Rats (Wag/Rij, females) were chronically treated with Losartan (20mg/d), an angiotensin II-receptor blocker during 9 months. Gene expression profiling was performed on aortic media to understand the long-term effect of this molecule on the cardiovascular system. Two-conditions experiment, Ctrl vs Losartan-treated animals. Biological replicates: 5 control replicates, 5 Losrtan-treated animals. All the RNA samples were pooled to provide a reference RNA for a two-color experiment.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Sophie Nadaud

PROVIDER: E-GEOD-18298 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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