CCAAT/enhancer-binding protein alpha target genes in myeloid progenitor cells uncovered by chromatin IP

ABSTRACT: CCAAT/enhancer-binding protein alpha (C/EBPM-NM-1) is a lineage-specific transcription factor that directs development of granulocytes. To obtain insights into the genome-wide transcriptome of wild type C/EBPM-NM-1, we have performed chromatin immunoprecipitation on DNA promoter microarrays (ChIP-chip) in the murine 32D myeloid progenitor cell line. These cells expressed an estradiol-inducible form of wild-type C/EBPM-NM-1. In the murine 32D myeloid progenitor cell line, expressing either an estradiol-inducible form of wild-type C/EBPM-NM-1. (C/EBPM-NM-1-ER, n=3, replicates), or as a control ER (n=2, replicates), we have performed chromatin immunoprecipitation on DNA promoter microarrays (ChIP-chip) after 4 hours of estradiol incubation.

ORGANISM(S): Mus musculus

SUBMITTER: Erdogan Taskesen 

PROVIDER: E-GEOD-19321 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress