Expression data of Streptococcus pneumoniae against penicillin

ABSTRACT: The increasing rate of penicillin resistance in S. pneumoniae in the early 1970s has resulted in therapeutic challenges and has prompted the need for alternative therapy in the management of pneumococcal infections. The development of penicillin resistance has been documented to be as a result of altered penicillin binding protein which alters the binding capacity of the drug to the organism. We used microarrays to investigate other genes which may be involved in the development of penicillin resistance in S. pneumoniae and identified classes of genes on the surface of the organism which may contribute to resistance. Strains of S. pneumoniae with varying initial susceptibility to penicillin were selected. These strains were grown to the logarithmic phase before being exposed to subinhibit

ORGANISM(S): Streptococcus pneumoniae

SUBMITTER: cheng foh le 

PROVIDER: E-GEOD-21709 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress