Dynamic transcriptomic profiles of zebrafish gills in response to zinc depletion

ABSTRACT: Zinc deficiency is detrimental to organisms highlighting its role as an essential micronutrient contributing to numerous biological processes. To investigate the underlying molecular events invoked by zinc depletion we performed a temporal analysis of transcriptome changes observed within zebrafish gill. This tissue represents a model system for studying ion absorption across polarised cells as it provides a major pathway for fish to acquire zinc directly from water whilst sharing a conserved zinc transporting system with mammals. Zebrafish were treated with either zinc-depleted (water = 2.61 μg L-1; diet = 26 mg kg-1) or zinc-adequate (water = 16.3 μg L-1; diet = 233 mg kg-1) conditions for two weeks. Gill samples were collected at five time points and transcriptome changes analysed in qu

ORGANISM(S): Danio rerio

SUBMITTER: Peter Kille 

PROVIDER: E-GEOD-21894 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress