Nucleosome positioning for 4 yeast species

ABSTRACT: We describe the genome-wide nucleosome profiles of four related yeast species. All species display the same global organization features first described in S. cerevisiae: a stereotypical nucleosome organization along genes, and the classification of promoters into these which contain or lack a pronounced Nucleosome Depleted region (NDR), with the latter displaying a more dynamic pattern of gene expression. This global similarity, however, does not reflect a static evolutionary pattern, as nucleosome positioning at specific genes diverged rapidly leaving practically no similarity between S. cerevisiae and C. glabrata orthologs (~50 Myr). We show that this rapid divergence in nucleosome positioning contrasts a conserved pattern of gene expression, consistent with the idea that divergence of

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Kyle Tsui 

PROVIDER: E-GEOD-23577 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress