Agricultural sterol biosynthesis inhibitor fungicides

ABSTRACT: Resistance to agricultural fungicides in the field has created a need for discovering fungicides with new modes of action. DNA microarrays, because they provide information on expression of many genes simultaneously, could help to identify the modes of action. To begin an expression pattern database for agricultural fungicides, transcriptional patterns of Saccharomyces cerevisiae strain S288C genes were analysed following 2-h treatments with I50 concentrations of ergosterol biosynthesis inhibitors commonly used against plant pathogenic fungi. Eight fungicides, representing three classes of ergosterol biosynthesis inhibitors, were tested. To compare gene expression in response to a fungicide with a completely different mode of action, a putative methionine biosynthesis inhibitor (MBI) was a

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Albrecht Michel 

PROVIDER: E-GEOD-2412 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress