Study of gene expression of mouse cMET experiments
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Chunsheng Zhang
PROVIDER: E-GEOD-25142 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting.
Lamb John R JR Zhang Chunsheng C Xie Tao T Wang Kai K Zhang Bin B Hao Ke K Chudin Eugene E Fraser Hunter B HB Millstein Joshua J Ferguson Mark M Suver Christine C Ivanovska Irena I Scott Martin M Philippar Ulrike U Bansal Dimple D Zhang Zhan Z Burchard Julja J Smith Ryan R Greenawalt Danielle D Cleary Michele M Derry Jonathan J Loboda Andrey A Watters James J Poon Ronnie T P RT Fan Sheung T ST Yeung Chun C Lee Nikki P Y NP Guinney Justin J Molony Cliona C Emilsson Valur V Buser-Doepner Carolyn C Zhu Jun J Friend Stephen S Mao Mao M Shaw Peter M PM Dai Hongyue H Luk John M JM Schadt Eric E EE
PloS one 20110705 7
<h4>Background</h4>In hepatocellular carcinoma (HCC) genes predictive of survival have been found in both adjacent normal (AN) and tumor (TU) tissues. The relationships between these two sets of predictive genes and the general process of tumorigenesis and disease progression remains unclear.<h4>Methodology/principal findings</h4>Here we have investigated HCC tumorigenesis by comparing gene expression, DNA copy number variation and survival using ∼250 AN and TU samples representing, respectively ...[more]
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