Comparison of EPC vs donor matched HUVEC

ABSTRACT: Background: In recent times a subset of bone marrow (BM) derived cells; endothelial progenitor cells (EPCs), have generated tremendous interest, as these cells are suggested to home to sites of neovascularization and neoendothelialization and differentiate into mature endothelial cells (ECs), a process referred to as postnatal vasculogenesis. EPCs are being considered as a potential regenerative tool for treating various pathophysiological disease states including cardiovascular disorder and as a possible target to restrict vessel growth in tumour pathology. However, conflicting results have been reported in the field due to lack of EPC specific biomarkers, and the identification, characterization, and the precise role of EPCs in vascular biology still remains a subject of great debate.

ORGANISM(S): Homo sapiens

SUBMITTER: Jyotsna Pippal 

PROVIDER: E-GEOD-25979 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress