Evolution of gene expression in the Drosophila melanogaster subgroup update and extension

ABSTRACT: http://www.nature.com/ng/journal/v33/n2/abs/ng1086.html. Little is known about broad patterns of variation and evolution of gene expression during any developmental process. Here we investigate variation in genome-wide gene expression among Drosophila simulans, Drosophila yakuba and four strains of Drosophila melanogaster during a major developmental transition?the start of metamorphosis. Differences in gene activity between these lineages follow a phylogenetic pattern, and 27% of all of the genes in these genomes differ in their developmental gene expression between at least two strains or species. We identify, on a gene-by-gene basis, the evolutionary forces that shape this variation and show that, both within the transcriptional network that controls metamorphosis and across the whole g

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Scott Rifkin 

PROVIDER: E-GEOD-2642 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress