Microarray analysis for M1SF370 Streptococcus pyogenes internalized in Detroit 562 human pharyngeal cells.

ABSTRACT: A total of 432 genes were found to be differentially expressed in M1SF370 bacterial population internalized in Detroit 562 human pharyngeal cells when compared with the same strain incubated in the absence of Detroit 562 cells. While most of them (349/432 i.e. 80.8%) were up regulated, 83 genes were down regulated contributing to 19.2% of the total differentiated genes. The major contributor of the latter category was phage-related genes (35 genes). Almost ¼ of these genes (106) belonged to a category of Unknown or possible predicted function. Most notably, up-regulated genes belonged to amino acid transport , cell division, cell envelope biogenesis, DNA replication correlated well with up-regulated 67 genes belonged to translation and ribosomal structure. Further, up-regulation of 12

ORGANISM(S): Streptococcus pyogenes

SUBMITTER: Vijay Pancholi 

PROVIDER: E-GEOD-27846 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress