Deep sequencing of pyrethroid-resistant bed bugs reveals multiple mechanisms of resistance within a single population

ABSTRACT: A frightening resurgence of bed bug infestations has occurred over the last 10 years in the US. Current chemical methods have been inadequate for controlling bed bugs due to widespread insecticide resistance. Little is known about the mechanisms of resistance present in US bed bug populations, making it extremely difficult to develop intelligent strategies to control this pest. We have identified bed bugs collected in Richmond, VA which exhibit both kdr-type (L925I) and metabolic resistance to pyrethroid insecticides. LD50 bioassays determined resistance ratios of ~6000-fold to the insecticide deltamethrin, with contact bioassays confirming cross-resistance to several other labeled formulations. To identify metabolic genes potentially involved in the detoxification of pyrethroids, we perfo

ORGANISM(S): Cimex lectularius

SUBMITTER: Zach Adelman 

PROVIDER: E-GEOD-31025 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress