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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptional profile of pathogenic and non-pathogenic in vitro generated mycobacterial cell wall deficient forms

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Mycobacterium avium subsp. paratuberculosis

SUBMITTER: Andrea Cossu

PROVIDER: E-GEOD-32237 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Unraveling the transcriptional regulatory networks associated to mycobacterial cell wall defective form induction by glycine and lysozyme treatment.

Rosu Valentina V Bandino Ennio E Cossu Andrea A

Microbiological research 20121126 3

It is known that a combined glycine/lysozyme treatment is able to induce in vitro the mycobacterial conversion from the bacillary to the cell wall defective forms. These forms also naturally occur in vivo as a response to various antimicrobial factors such as lysozyme released by phagocytic cells. Although they have been successfully isolated from patients with several chronic diseases, their role in pathogenesis is still unknown, mainly due to the difficulties in handling the in vivo isolated v ...[more]

PMID: 23195184

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