Vastus lateralis muscle gene expression after local physical deconditioning and exercise training
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ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Gerwen Lammers
PROVIDER: E-GEOD-33886 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Expression of genes involved in fatty acid transport and insulin signaling is altered by physical inactivity and exercise training in human skeletal muscle.
Lammers Gerwen G Poelkens Fleur F van Duijnhoven Noortje T L NT Pardoel Elisabeth M EM Hoenderop Joost G JG Thijssen Dick H J DH Hopman Maria T E MT
American journal of physiology. Endocrinology and metabolism 20120925 10
Physical deconditioning is associated with the development of chronic diseases, including type 2 diabetes and cardiovascular disease. Exercise training effectively counteracts these developments, but the underlying mechanisms are largely unknown. To gain more insight into these mechanisms, muscular gene expression levels were assessed after physical deconditioning and after exercise training of the lower limbs in humans by use of gene expression microarrays. To exclude systemic effects, we used ...[more]
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