Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Expression data from transfection of U87 glioma cells with miR-376a* for 72 hours


ABSTRACT: Several biological pathways can be under the regulation of miRNAs. These pathways can be indentified by the enforced expression of a miRNA and analysing the expression data for enrichment of specific pathways represented among the genes differentially expressed upon miRNA overexpression. We transfected unedited miR-376a* (376a*A) and edited miR-376a* (376a*G) into U87 cells to identify differentially regulated transcripts. List of differentially expressed genes were subject to pathway enrichment analysis to identify specific biological processes regulated by each of miR-376a*A and miR-376a*G. U87 cells (100,000) were transfected with 50 nM of miR-376a*A, miR-376a*G or miR-control. Following incubation for 72 hours, total RNA was isolated from transfected cells. For each (miR-376a*A or miR-

ORGANISM(S): Homo sapiens

SUBMITTER: Yukti Choudhury 

PROVIDER: E-GEOD-34456 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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