Transcriptome of Protoplasts Reprogrammed into Stem Cells in Physcomitrella patens

ABSTRACT: We obtained genome-wide digital gene expression tag profiles within the first three days of P. patens protoplast reprogramming. At four time-points during protoplast reprogramming, the transcript levels of 4827 genes changed more than four-fold and their expression correlated with the reprogramming phase. Gene ontology (GO) and pathway enrichment analysis of differentially expressed genes (DEGs) identified a set of significantly enriched GO terms and pathways, most of which were associated with photosynthesis, protein synthesis and stress responses. DEGs were grouped into six clusters that showed specific expression patterns using a K-means clustering algorithm. An investigation of function and expression patterns of genes identified a number of key candidate genes and pathways in early st

ORGANISM(S): Physcomitrella patens

SUBMITTER: Lihong Xiao 

PROVIDER: E-GEOD-36117 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress