Genome sequecing of yeast strain evolved under high glucose

ABSTRACT: A population of Saccharomyces cerevisiae was cultured for approximately 450 generations in the presence of high glucose to select for genetic variants. This experiment allows for a controlled model of adaptive evolution under natural selection. Using the parental strain BY4741 as the starting population, an evolved culture was obtained after continuous aerobic growth in a glucose-high medium for approximately 450 generations. After the evolution period three single colony isolates were selected for analysis. Next-generation Ion Torrent sequencing was used to evaluate genetic changes. Greater than 100 deletion/insertion changes were found with approximately half of these effecting genes. Additionally, over 180 single-nucleotide polymorphisms (SNPs) were identified with more than one quar

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Anthony Aragon 

PROVIDER: E-GEOD-36518 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress