Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

IM010 - Infection with A/Vietnam/1203/04 H5N1 influenza virus of C57BL/6J mice, IDO1 KO mice or TNFRSF1B KO mice


ABSTRACT: Comparison of the host response to VN1203 infection in three different strains of mice: Wild-type C57BL/6J mice, IDO1 KO mice and TNFRSF1B KO. Groups of 6-week-old mice were infected with A/Vietnam/1203/04 H5N1 influenza virus at a dose of 10^3 PFU or mock infected. Mice were euthanized on days 2 and 6 post-infection to measure virus load and isolate samples for measurement of virus load, lung pathology, transcriptional analysis and proteomics analysis. Mock-infected animals were also harvested at each time point. Mice were weighed every 24 hours to measure general disease progression and any mouse approaching 30% weight loss was euthanized.

ORGANISM(S): Mus musculus

SUBMITTER: Richard Green 

PROVIDER: E-GEOD-40792 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2012-02-20 | E-GEOD-35940 | biostudies-arrayexpress
2012-09-13 | E-GEOD-40844 | biostudies-arrayexpress
2012-02-21 | E-GEOD-35943 | biostudies-arrayexpress
2012-02-20 | E-GEOD-35933 | biostudies-arrayexpress
2012-05-13 | E-GEOD-37829 | biostudies-arrayexpress
2012-05-13 | E-GEOD-37951 | biostudies-arrayexpress
2012-02-13 | E-GEOD-35738 | biostudies-arrayexpress
2012-08-13 | E-GEOD-40092 | biostudies-arrayexpress
2012-02-15 | E-GEOD-35816 | biostudies-arrayexpress
2014-02-20 | E-GEOD-50878 | biostudies-arrayexpress