Time-course expression data during assurance of the chronological longevity by caloric restriction in budding yeast

ABSTRACT: Caloric restriction (CR) is the only non-genetic intervention to retard aging and increase longevity in a variety of species. It is important to understand the fundamental mechanism by which CR extends lifespan that remains elusive. Owing to well-established genomic tools and convenience of culture system, we used a single cell organism, Saccharomyces cerevisiae, to clarify the mechanisms of CR. In order to identify genes responsible for CR-mediated longevity, we performed microarray experiments across the longevity assurance time-points. Since the CR-treated cells obtained the longevity potential around 12 hours after inoculation and the strength of potential gradually increased up to 48 hours, we concluded that the changes across these time-points must be a critical need for assurance of

ORGANISM(S): Saccharomyces cerevisiae BY4741

SUBMITTER: Cheol-Koo Lee 

PROVIDER: E-GEOD-41860 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress