Transcriptional profiling of nhr-114 vs. glp-1 animals, and wild type + Trp vs. wild type animals.

ABSTRACT: Animals can thrive on variable food resources as a result of autonomous processes and beneficial relationships with their gut microbes. Food intake elicits major physiological changes, which are compensated with transient systemic responses that maintain homeostasis in the organism. This integration of external information occurs through cellular sensory elements, such as nuclear receptors, which modulate gene expression in response to specific cues. Given the importance of the germline stem cells (GSCs) for the development of the germ line and the continuity of the species, it is reasonable to assume that GSCs might be shielded from the negative influence of environmental perturbations. To our knowledge, however, there are no mechanisms reported that protect proliferating germ cells from

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Xicotencatl Gracida 

PROVIDER: E-GEOD-43864 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress