Transcription profiling of human Treg cell versus their controls in human and mouse

ABSTRACT: We applied Affymetrix GeneChip technology for expression profiling of CD4+CD25+ (Treg) T cells versus their naive CD4+CD25- controls to obtain more information about the underlying molecular mechanisms involved in Treg specific immune suppression Experiment Overall Design: Expression profiles from: Experiment Overall Design: [1] human Treg cells obtained from peripheral blood by cell sorting were compared to their naive controls. RNAs were prepared from pools of ten individual healthy donors, labeled in two independend labeling reactions and hybridized onto two GeneChips of the same lot. Experiment Overall Design: [2] mouse Treg cells obtained from spleen by cell sorting of Balb/c mice were compared to their naive controls. RNAs were prepared from pools of three individual Balb/c mice, l

ORGANISM(S): Mus musculus

SUBMITTER: Robert Geffers 

PROVIDER: E-GEOD-4571 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress