Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Robert Geffers
PROVIDER: E-GEOD-4571 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Pfoertner Susanne S Jeron Andreas A Probst-Kepper Michael M Guzman Carlos A CA Hansen Wiebke W Westendorf Astrid M AM Toepfer Tanja T Schrader Andres J AJ Franzke Anke A Buer Jan J Geffers Robert R
Genome biology 20060101 7
<h4>Background</h4>Naturally occurring CD4+ CD25+ regulatory T cells (TReg) are involved in the control of autoimmune diseases, transplantation tolerance, and anti-tumor immunity. Thus far, genomic studies on TReg cells were restricted to murine systems, and requirements for their development, maintenance, and mode of action in humans are poorly defined.<h4>Results</h4>To improve characterization of human TReg cells, we compiled a unique microarray consisting of 350 TReg cell associated genes (H ...[more]