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Genome-wide differential gene expression signatures in pediatric acute lymphoblastic leukemia subtypes

ABSTRACT: We surveyed the genome-wide DNA methylation levels and gene expression patterns in patients with pediatric acute lymphoblastic leukemia. Using Affymetrix U133 Plus 2.0 GeneChips, we identified a relatively small set of CpG sites that are highly correlated with gene expression. Genome-wide expression analysis of 108 primary ALL samples by Affymetrix Human Genome U133 Plus 2.0 GeneChips used to investigate relationships between subtype-specific DNA methylation patterns and gene expression in 93 patients with both gene expression and DNA methylation data.

ORGANISM(S): Homo sapiens

SUBMITTER: Jessica Nordlund

PROVIDER: E-GEOD-47051 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Genome-wide differential gene expression signatures in pediatric acute lymphoblastic leukemia subtypes

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