Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genome-wide differential gene expression signatures in pediatric acute lymphoblastic leukemia subtypes

ABSTRACT: We surveyed the genome-wide DNA methylation levels and gene expression patterns in patients with pediatric acute lymphoblastic leukemia. Using Affymetrix U133 Plus 2.0 GeneChips, we identified a relatively small set of CpG sites that are highly correlated with gene expression. Genome-wide expression analysis of 108 primary ALL samples by Affymetrix Human Genome U133 Plus 2.0 GeneChips used to investigate relationships between subtype-specific DNA methylation patterns and gene expression in 93 patients with both gene expression and DNA methylation data.

ORGANISM(S): Homo sapiens

SUBMITTER: Jessica Nordlund

PROVIDER: E-GEOD-47051 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Shared Molecules

Only show the datasets with similarity scores above: 0.5

Threshold

0.5

Similar Datasets

Genome-wide differential gene expression signatures in pediatric acute lymphoblastic leukemia subtypes

Project description:We surveyed the genome-wide DNA methylation levels and gene expression patterns in patients with pediatric acute lymphoblastic leukemia. Using Affymetrix U133 Plus 2.0 GeneChips, we identified a relatively small set of CpG sites that are highly correlated with gene expression.

2013-09-18 | GSE47051 | GEO

Affymetrix striptease

Project description:new and stripped chips Keywords: reuse of Affymetrix GeneChips U133 Plus 2.0

2005-08-20 | GSE2833 | GEO

Rhesus Macaque gene expression data obtained using Rhesus Macaque Array or Human Genome U133 Plus 2.0 Array

Project description:The primary goal of this study was to compare the performances of Rhesus Macaque Genome Array and Human Genome U133 Plus 2.0 Array with respect to the detection of differential expressions when rhesus macaque RNA extracts were labeled and hybridized. The secondary goal of this study was to investigate the effect of mismatch position on signal strength in Affymetrix GeneChips by examining naturally occurring mismatches between rhesus macaque transcripts and human probes from Human Genome U133 Plus 2.0 Array. The primary goal of this study was to compare the performances of Rhesus Macaque Genome Array and Human Genome U133 Plus 2.0 Array with respect to the detection of differential expressions when rhesus macaque RNA extracts were labeled and hybridized. The secondary goal of this study was to investigate the effect of mismatch position on signal strength in Affymetrix GeneChips by examining naturally occurring mismatches between rhesus macaque transcripts and human probes from Human Genome U133 Plus 2.0 Array. Keywords: cross hybridization

2008-06-15 | GSE9531 | GEO

Genes regulated by HS3ST2

Project description:We used Affymetrix HG U133 Plus 2.0 GeneChips to compare the transcriptome of HS3ST2-transfected and control vector-transfected MDA-MB-231 cells.

2016-08-15 | GSE49962 | GEO

Genes regulated by SDC1 in Caco-2 cells

Project description:We used Affymetrix HG U133 Plus 2.0 GeneChips to compare the transcriptome of Caco-2 cells transfected with SDC1-siRNA against negative control siRNA-transfected cells.

2020-05-14 | GSE58751 | GEO

Genes regulated by SDC1

Project description:We used Affymetrix HG U133 Plus 2.0 GeneChips to compare the transcriptome of MDA-MB-231 cells transfected with SDC1-siRNA against negative control siRNA-transfected cells.

2013-08-01 | GSE23362 | GEO

Genes regulated by miR-145

Project description:We used Affymetrix HG U133 Plus 2.0 GeneChips to compare the transcriptome of miR-145-overexpressing MDA-MB-231 cells against negative control miRNA precursor-transfected cells.

2010-09-07 | GSE19737 | GEO

Global expression data from HCT-116 human colorectal cancer (CRC) wild type cells (HCT116/GFP) and CPEB4 over-expressed cells via lenti-virus system (HCT116/CPEB4)

Project description:CPEB4 is down-regulated in CRC tissues, a stable cell line was established via lenti-virus system for CPEB4 overexpression. Microarray experiment by the Affymetrix Human Genome U133 plus 2.0 GeneChips to examine the profiling expression of indicated cells.

2023-03-04 | GSE226251 | GEO

An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer: gene expression

Project description:10 Breast cancer cell lines profiled on the Affymetrix U133 Plus 2.0 platform used in conjunction with matched DNA copy number and DNA methylation data for integrative analysis.

2010-11-05 | GSE17768 | GEO

DNA methylation and gene expression analysis during myogenic differentiation

Project description:DNA methylation has been considered to play an important role during myogenic differentiation. In terminal differentiation of myoblasts, chronological alteration of DNA methylation status was poorly understood. Using Infinium HumanMethylation450 BeadChips, we validated genome wide DNA methylation profiles of human myoblast differentiation models. To investigate correlation between DNA methylation and gene expression, we also assessed gene expression of myoblasts with GeneChip Human Genome U133 Plus 2.0 array.

2014-02-15 | GSE55034 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data