High-throughput sequencing reveals differential expression of miRNAs in intestine from sea cucumber during aestivation [microarray]

ABSTRACT: The regulatory role of miRNA in gene expression is an emerging hot new topic in the control of hypometabolism. Sea cucumber aestivation is a complicated physiological process that includes obvious hypometabolism as evidenced by a decrease in the rates of oxygen consumption and ammonia nitrogen excretion, as well as a serious degeneration of the intestine into a very tiny filament. To determine whether miRNAs play an important regulatory roles in this process, the present study analyzed profiles of miRNA expression in the intestine of sea cucumber (Apostichopus japonicus), using Solexa deep sequencing technology. We identified 309 sea cucumber miRNAs, including 19 novel miRNAs specific to sea cucumber. Animals sampled during deep aestivation (DA) after at least 15 days of continuous torpor,

ORGANISM(S): Apostichopus japonicus

SUBMITTER: Muyan Chen 

PROVIDER: E-GEOD-48868 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress