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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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AR and c-Myb depletion effects in prostate cancer cells

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Timothy Thompson

PROVIDER: E-GEOD-49287 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Genome-wide analysis of AR-responsive gene expression in prostate cancer cells

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Genome-wide analysis of c-Myb-responsive gene expression in prostate cancer cells

Project description:Analysis of c-Myb-regulation of gene expression. The hypothesis tested in the present study was that c-Myb influences the expression of specific sets of genes that are involved in cell cycle, DNA replication, recombination and repair. Results provide important information on c-Myb-responsive genes that may be crucial to the cell survival and the progression of prostate cancer. Total RNA obtained from c-Myb siRNA-transfected prostate cancer cells compared to negative control siRNA-transfected prostate cancer cells 48 h after siRNa transfection.

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AR and c-Myb depletion effects in prostate cancer cells

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