Cerebellar Gene Expression Profile Analysis in a Rat Model of Acute Alcohol Intoxication

ABSTRACT: To identify possible target molecules for acute alcohol intoxication therapy, we used microarray analysis to compare cerebella gene expression profiles of control and acute alcohol-intoxicated rats. We first established a model of acute alcohol intoxication in SD rats, and then used rat cDNA microarray to profile mRNA expression in the cerebella of alcohol-intoxicated rats (experimental group) and saline-treated rats (control group). A six chip study using total RNA recovered from three separate experimental groups and three separate control groups. We first established a model of acute alcohol intoxication in SD rats, and then used rat cDNA microarray to profile mRNA expression in the cerebella of alcohol-intoxicated rats (experimental group) and saline-treated rats (control group). Cereb

ORGANISM(S): Rattus norvegicus

SUBMITTER: Ji-lai Liu 

PROVIDER: E-GEOD-49303 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress