Dose- and time- dependent ionizing ratidation effect on mice peripheral blood

ABSTRACT: Gene expression profiles of peripheral blood samples from C57BL/6 mice exposed with ionizing radiation. We used mice as model animal to study biologial recovery response after radiation damage. Therefore, we obtained gene expression profiles from C57BL/6 mice exposed with various levels of ionizing radiation, including low and high doses and control groups. In order to measure recovery rate, we collected peripheral blood samples at different time durations after the exposure. In order to obtain robust signatures specific to radiation response, we are interested in knowing if the radiation signarures will be present in the presence of confounders. Therefore, mice were given intraperitoneal injections of lipopolysaccharide endotoxin (LPS), or treated with granulocyte colony-stimulating fact

ORGANISM(S): Mus musculus

SUBMITTER: lingling zheng 

PROVIDER: E-GEOD-52403 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress