Effects of RNAi protein overexpression in mutant cells on H3K9 dimethylation in fission yeast cells

ABSTRACT: We test the effects of overexpressing RNAi proteins Dcr1, Rdp1, or Ago1 in wildtype, dcr1M-bM-^HM-^F, ago1M-bM-^HM-^F, or rdp1M-bM-^HM-^F cells. We find that overexpression does not generally affect H3K9me2 at euchromatic loci, but there are varying effects in H3K9me2 on centromeric heterochromatin. Examination of genome-wide enrichment in H3K9 dimethylation in fission yeast haploid cells

ORGANISM(S): Schizosaccharomyces pombe

SUBMITTER: Ruby Yu 

PROVIDER: E-GEOD-52444 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress