Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs


ABSTRACT: We utilized next generation sequencing of transcripts (RNA-seq) to characterize the SLE transcriptome in monocytes.This is the first RNA-seq study of SLE using clinical subjects and we found a transcriptome that exhibits quantitative alterations as defined by the level of gene expression but also qualitative differences with widely altered splicing preference and non-coding RNA transcription. total RNA from 8 heathy controls and 9 SLE patients were used to RNA sequence and comparision the whole transcriptome alteration

ORGANISM(S): Homo sapiens

SUBMITTER: Kathleen Sullivan 

PROVIDER: E-GEOD-53419 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2016-08-01 | E-GEOD-83843 | biostudies-arrayexpress
2016-02-26 | E-GEOD-78506 | biostudies-arrayexpress
2014-05-13 | E-GEOD-57567 | biostudies-arrayexpress
2024-01-01 | E-MTAB-5752 | biostudies-arrayexpress
2014-06-03 | E-GEOD-46913 | biostudies-arrayexpress
2016-04-01 | E-GEOD-73082 | biostudies-arrayexpress
2016-04-01 | E-GEOD-73083 | biostudies-arrayexpress
2015-01-09 | E-GEOD-64795 | biostudies-arrayexpress
2014-06-03 | E-GEOD-46920 | biostudies-arrayexpress
2014-06-03 | E-GEOD-46917 | biostudies-arrayexpress