Mapping of Hepatic Expression Quantitative Trait Loci (eQTLs) in a Han Chinese Population [SNP analysis]

ABSTRACT: Elucidating the genetic basis underlying the variation in hepatic gene expression is of importance to understand disease etiology and drug metabolism variances. To date, no genome-wide eQTL analysis has been conducted in the Han Chinese, the largest ethnic group in the world. We performed a genome-wide eQTL mapping in a set of Han Chinese liver tissue (n=64). Normal (non-diseased) liver tissues were previously collected from 64 Chinese donors who provided informed consent. All samples were stored frozen at -80℃ from collection until processing for RNA and DNA extraction. DNA /Total RNA of the human liver tissue samples were extracted by using the RNA/DNA Mini Kit (Qiagen, Hilden, Germany).each RNA sample were labeled and hybridized to the One-Color Agilent 60-mer Whole Human Genome Microar

ORGANISM(S): Homo sapiens

SUBMITTER: Zhiqiang Li 

PROVIDER: E-GEOD-53790 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress