Negative energy balance and splenic gene expression patterns in high yielding dairy cows during the early postpartum period [spleen]

ABSTRACT: Increased energy demands to support lactation, coupled with lowered feed intake capacity results in negative energy balance (NEB) and is typically characterized by extensive mobilization of body energy reserves in the early postpartum dairy cow. The catabolism of stored lipid leads to an increase in the systemic concentrations of nonesterified fatty acids (NEFA) and -hydroxy butyrate (BHB). Oxidation of NEFA in the liver result in the increased production of reactive oxygen species and the onset of oxidative stress and can lead to disruption of normal metabolism and physiology. The immune system is depressed in the peripartum period and early lactation and dairy cows are therefore more vulnerable to bacterial infections causing mastitis and or endometritis at this time. A bovine Affymet

ORGANISM(S): Bos taurus

SUBMITTER: Dermot Morris 

PROVIDER: E-GEOD-56589 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress