The transcriptomic profile of Pseudozyma aphidis during production of mannosylerythritol lipids

ABSTRACT: Pseudozyma aphidis is one of the most productive microbial producers of mannosylerythritol lipids on vegetable oils with a unique product spectrum that contains all four main variants MEL-A, -B, -C and -D. Secretion of MEL is thereby accompanied by a morphologenetic switch from yeast to hyphal growth. To investigate the genetic characteristics of MEL secretion and dimorphic transition, we analyzed the transcriptome of P. aphidis during production of MEL after the morphologenetic switch. The analysis revealed that the strong activation of 4 of the 5 genes within the MEL-cluster is clearly dependent on the presence of a hydrophobic carbon source. Only the acetyltransferase mat1 is not induced. This may explain the heterogeneous mixture of MEL with different degree of acetylation. In parallel

ORGANISM(S): Pseudozyma aphidis

SUBMITTER: Kai Sohn 

PROVIDER: E-GEOD-57014 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress