Quantitative analysis of wild type and MeCP2-/y mice hippocampus miRNAs using next generation sequencing

ABSTRACT: To determine whether the miRNA expression profile is altered by MeCP2, we performed Solexa-based RNA sequencing(RNA-seq) to assess global changes in the expression pattern of miRNAs caused by the loss of MeCP2 in mecp2 null (knockout[KO]) mice (Chen et al., 2001). Hippocampus miRNA profiles of 30-day old wild type (WT) and MeCP2-/y mice were generated by deep sequencing using Illumina HiSeq 2000

ORGANISM(S): Mus musculus

SUBMITTER: Zilong Qiu 

PROVIDER: E-GEOD-59029 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress