Centromere misdivision promotes centromeric sequence changes, de novo centromere formation, and centromere expansion

ABSTRACT: Centromeres typically contain repeat sequences, but centromere function does not necessarily depend on these sequences. In aneuploid wheat (Triticum aestivum) and wheat distant hybridization offspring, we found functional centromeres with dramatic changes to centromeric retrotransposon of wheat (CRW) sequences. CRW sequences were greatly reduced in the ditelosomic lines 1BS, 5DS, 5DL, and a wheat-Thinopyrum elongatum addition line. CRWs were completely lost in the ditelosomic line 4DS, but a 994 kb ectopic genomic DNA sequence was involved in de novo centromere formation on the 4DS chromosome. In addition, two ectopic sequences were incorporated in a de novo centromere in a wheat-Th. intermedium addition line. Centromeric sequences were also expanded to the chromosome arm in wide hybridiza

ORGANISM(S): Triticum aestivum

SUBMITTER: Handong Su 

PROVIDER: E-GEOD-63752 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress