Genes regulated in EML1 cells expressing the TEL-AML1 oncogene after 5 and 7 days of treatment with IL7 and FLT3 ligand.

ABSTRACT: The t(12;21) translocation is the most common genetic rearrangement in childhood acute lymphoblastic leukemia (ALL) and gives rise to the TEL-AML1 fusion gene, which functions as a transcription factor. TEL-AML1 expression in EML1 cells results in an impairment of differentiation along the B-lymphoid lineage. We analyzed gene expression profiles of EML1 cells after expression of TEL-AML1

ORGANISM(S): Mus musculus

SUBMITTER: Myriam Alcalay 

PROVIDER: E-GEOD-64919 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress