Changes in global gene expression of Vibrio parahaemolyticus viable but non-culturable (VBNC) state

ABSTRACT: The phenomenon of viable but non-culturable (VBNC) referred as a dormant state of non-sporulating bacteria enhancing the survival in adverse environments. To our knowledge, only few studies have been performed on whole genomic expression of V. parahaemolyticus in VBNC state compared with cells in exponential and early stationary phases. Since many VBNC state studies found DNA, RNA and protein degradation, we hypothesise that gene regulation of VBNC cells is highly reduced, down-regulation of gene expression is dominant and only metabolic functions crucial for survival are kept on a sustained basis. In the VBNC state we found 509 significantly induced genes and 309 significantly repressed by more than twofold compared with unstressed phases among 4820 investigated genes (adjusted P-value <

ORGANISM(S): Vibrio parahaemolyticus RIMD 2210633

SUBMITTER: Stephan Huehn 

PROVIDER: E-GEOD-65340 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress