Unknown,Transcriptomics,Genomics,Proteomics

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Two human HCC cells (MHCC97H and MHCC97L): PML-siRNA transfected vs. control

ABSTRACT: We found PML was responsible for ATO resistance in HCC cells, PML knockdown cells show better sensitivity to ATO treatment. To further explore the mechanism of PML-induced ATO resistance, we performed a microarray assay to compare the differential gene expression profiles of PML-siRNA-treated (PML knockdown) and negative control siRNA-treated cells. Two-condition experiment, PML-siRNA vs. control cells. Biological replicates: two cell lines and each cell line has 1 control, 1 transfected, independently grown and harvested. One replicate per array. Comparisons were made between PML siRNA group and control group for each cell line

ORGANISM(S): Homo sapiens

SUBMITTER: Xin Zhang

PROVIDER: E-GEOD-67574 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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