Transcriptomic analysis of glycolaldehyde-treated wild type cells and a synthetic strain

ABSTRACT: A synthetic pathway for (D)-xylose assimilation was stoichiometrically evaluated regarding its potential to produce selected value-added compounds and implemented in Escherichia coli strains. The pathway proceeds via the isomerization of (D)-xylose to (D)-xylulose, the phosphorylation of (D)-xylulose to obtain (D)-xylulose-1-phosphate (Xyl1P), and the aldolase cleavage of the latter to yield glycolaldehyde and DHAP. Both compounds can be further processed via the annotated natural metabolic network. Stoichiometric analyses showed that the synthetic pathway provides an efficient access to the value-added two-carbon (C2) compounds ethylene glycol and glycolic acid, which are either inaccessible via the annotated metabolic network of E. coli or produced at 20 % lower theoretical yield, respec

ORGANISM(S): Escherichia coli

SUBMITTER: Ceren Alkim 

PROVIDER: E-GEOD-69265 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress